Studies included in this database:

LinkPubMed IDTitle:AuthorsExperiment typeJournalDriversTissuesTargets
Marcotte(2012) 22585861 Essential gene profiles in breast, pancreatic, and ovarian cancer cells. Marcotte R, Brown KR, Suarez F et al shRNA Cancer Discovery 11 3 16028
Cowley(2014) 25984343 Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Cowley GS, Weir BA, Vazquez F, et al shRNA Scientific Data 45 9 5013
Marcotte(2016) 26771497 Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance. Marcotte R, Sayad A, Brown KR, et al shRNA Cell 21 1 15697
Campbell(2016) 26947069 Large Scale Profiling of Kinase Dependencies in Cancer Cell Line Campbell J, Ryan CJ, Brough R, et al siRNA Cell Reports 18 6 714
Wang(2017) 28162770 Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras Wang T, Yu H, Hughes NW, Liu B et al CRISPR Cell 5 1 18664