Studies included in this database:

LinkPubMed IDTitle:AuthorsExperiment typeJournalDriversTissuesTargets
Marcotte(2012) 22585861 Essential gene profiles in breast, pancreatic, and ovarian cancer cells. Marcotte R, Brown KR, Suarez F et al shRNA Cancer Discovery 11 2 16028
Marcotte(2016) 26771497 Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance. Marcotte R, Sayad A, Brown KR, et al shRNA Cell 21 1 15697
Campbell(2016) 26947069 Large Scale Profiling of Kinase Dependencies in Cancer Cell Line Campbell J, Ryan CJ, Brough R, et al siRNA Cell Reports 18 6 714
Wang(2017) 28162770 Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras Wang T, Yu H, Hughes NW, Liu B et al CRISPR Cell 5 1 18664
Tsherniak(2017) 28753430 Defining a Cancer Dependency Map. Tsherniak A, Vazquez F, Montgo et al shRNA Cell 89 11 17098
McDonald(2017) 28753431 Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening McDonald ER 3rd, de Weck A, Sc et al shRNA Cell 84 12 7837
Meyers(2017) 29083409 Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. Meyers RM, Bryan JG, McFarland et al CRISPR Nat Genet 63 10 17671